섬유

Hyperreactibity and Atopy Among Asthmatic Ex-Cotton Workers.

  • 출판일1995.05
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 587
An experiment characterized bronchial hyperreactivity among asthmatic subjects who had worked at cotton spinning mills in Denmark. THe study evaluated ten subjects, including nine smokers and one nonsmoker. None had a previous history of asthma. The subjects averaged 26.3 years in age, their mean employment time was 15.7 months, and the mean time of symptom onset was 5.6 months. Tests included eosinophil count, RAST (cotton dust, bract, mites, and endotoxins) reactivity, Wards mold precipitin count, percent lung founction, and histamine PC20 level. All the subjects exhibited bronchial hyperreactivity to endotoxin with an mean hestamine PC20 of 1.6 milligrams per milliliter. Results indicated that the cotton dust laden atmosphere in the Danish spinning mills initiated nonallergenic bonchial hyperreactivity in the subjects, which subsequently led to symptomatic asthma. 8 refs.
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