섬유

dietary protein effects on cholelithiasis in hamsters: interaction with amino acids and bile acids

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 351
the objective of this experiment was to study the effects of dietary cottonseed protein and casein on plasma and biliary lipids, plasma amino acids and gallstones in hamsters. thirty-four male hamsters (60 $plus or minus$ 5 g) were fed either the lithogenic 'dam diet' (containing 20 casein, 74. 3 sucrose and 5. 7 vitamin-mineral mix) or a similar diet that contained 20 cottonseed protein for 30 days. both diets contained protein as a protein isolate. the concentration of alpha-aminobutyric acid was significantly elevated in the casein-fed group. it is proposed that cottonseed protein may have a specific effect on the bile acid pool by increasing the ratio of glycochenodeoxychlolic acid:glycoholic acid which, in turn, prevents formation of cholesterol gallstones (edited author abstract) 38 refs
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