섬유

glucose biosensors based on thick film technology

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 314
various techniques for the fabrication of thick film biosensors are described. with electrodes printed on conventional thick film substrates, glucose is measured via the formation of hydrogen peroxide using glucose oxidase. additional diffusion barriers extend the linear range of the sensor up to 15 mm. using a new, flexible, unfired substrate material sensors with a three-dimensional structure can be made. the resulting cavities can be filled with carbon paste hence, the mediator technique and the use of dehydrogenases was applied to the fabrication of thick film biosensors. the linear range, sensitivity and stability of these sensors is strongly dependent on preparation methods such as the immobilization technique (mediated electrode) and the amount of cofactor and enzyme. without any diffusion barrier the linear range is limited to about 1 mm for the sensor based on the dehydrogenase. (author abstract) 19 refs
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