섬유

transducer mechanisms for optical biosensors. part 1. the chemistry of transduction

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 316
the first stage of optical biosensor transduction involves a chemical interaction between the analyte and an indicator phase to produce an optically detectable signal. this stage is critical because it determines stability, selectivity and sensitivity as well as establishing the wavelengths required for the optical measurement several types of analyte/indicator interaction are possible. direct indicators such as those used in optical ph sensors are in equilibrium with the analyte in the sample. they may be used for continuous measurements and can be coupled to the sensing of other analytes such as acidic and basic gases like carbon dioxide and ammonia. sensors based on catalysis by an immobilised enzyme involve a steady-state measurement of optically detectable substrate or product. high selectivity can be achieved using antibodies as reagents and basing sensing on competitive binding. (edited author abstract) 56 refs
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