섬유

macromolecular release from collagen monolithic devices

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 294
collagen monolithic devices varying in crosslinking density, collagen structure, and crosslinker were fabricated. proteolytic enzymes did not degrade the collagen devices; the degradation rate with collagenase was dependent on collagen structure, crosslinker, crosslinking density, and enzyme concentration. in vivo biocompatibility, degradation, and **1**4c-inulin release rates were evaluated subcutaneously in rats. after 3 weeks, none of the collagen discs induced any severe cellular response. (edited author abstract) 12 refs
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