섬유

studies on the $beta$ -turn of peptides. v. turn preference of peptide sequences analyzed by conformational energy calculation on dipeptide models and by cd spectra of chromophoric derivatives

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 227
empirical conformational energy calculations were performed on ac-l-pro-d-ala-nhch//3 and ac-d-ala-l-pro-nhch//3. in order to study the turn tendency of the dipeptide sequences turn probabilities and average interterminal distances were calculated. much larger turn preference of d-ala containing sequences was indicated compared with the corresponding l-ala containing sequences. the turn tendency of the dipeptide sequences were shown to be in the order: l-pro-d-ala $greater than$ d-ala-l-pro $greater than$ l-prol-ala $greater than$ l-ala-l-pro. this order coincides with the order of the magnitude of the cotton effects in the cd spectra of the chromophoric derivatives having 2,4-dinitrophenylglycyl and glycine-p-nitroanilide at the n- and the c-termini, respectively, of the corresponding dipeptide sequences using chromophoric derivatives reported earlier. 13 refs
이전글 다음글 목록