비의류제품

lb film immobilized immunosensor with a charge detection type amplifier

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 453
in order to fabricate a miniaturized solid-state sensor, a novel potentiometric immunosensor was designed by incorporating a new amplification system of charge detection type and an electrode covered with immunoglobulin-g (igg, antigen) immobilized in a langmuir-blodgett (lb) film. a surface potential change of 1 mu v generated by the immuno-reaction between igg and anti-igg (antibody) could be measured with the amplification system, which made it possible to detect the anti-igg with concentrations less than 5*10/sup -8/ m. the intensity of surface potential change observed in the reaction was successfully correlated with the activity of the immobilized igg by using luminescent enzyme immunoassay
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