비의류제품

development of a small gantry robotic workcell for deoxyribonucleic acid (dna) filter array construction

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 545
at los alamos national laboratory, we have constructed a primary cosmid library of human chromosome 16. this library consists of an 11-fold representation of the chromosome and is arrayed in microtiter plate format. a need has arisen in the large scale physical mapping of this chromosome, to array spots of dna from each of these colonies onto filter media for hybridization studies. we are currently developing a small gantry robot-based workcell to array small spots of dna in an interleaved format. this allows for the construction of a high spot density format filter array. this paper will discuss the features incorporated into this workcell for the handling of thousands of colonies and their automatic tracking and positioning onto the filter. 7 refs., 3 figs., 1 tab