three new glass-ceramics have been prepared based on calcium phosphates. each of them is classified into three typical categories of glass-ceramics, i.e., (1) volumely crystallized dense glass-ceramics with a composition of 45 cao.25 tio2.30p2o5(mol ) or 52 cao.al2o3.47p2o5(+5zro2 && 0.5y203), (2) uni-directionally crystallized glass-ceramics composed of beta-ca (po3)2 crystalline fibers alligned in parallel to the rod axis, and (3) microporous glass-ceramics with a cati4 (po4)6 skeleton. glass ceramics (1) are promising as a material for castable dental crowns because their excellent shapability and mechanical properties. the unidirectionally crystalized ca (po3)2 glass-ceramics (2) have extremely high toughness and flexibility like natural bones, both of which are quite unique as ceramics. the biocompatibility may be improved effectively by formation of apatite phases on their surfaces by chemical treatments. glass-ceramics (3) is the first microporous glass-ceramics with a skeleton of non-silicate crystals. the median pore diameter is 30 nm and the specific surface area and porosity are 50 sq m and 50 vol , respectively. the material is durable in both acid and alkaline solution. the applications to biotechnology such as enzyme carriers are expected