비의류제품

differential modulation of single voltage-gated calcium channels by cholinergic and adrenergic agonists in adult hippocampal neurons reprint: differential modulation of single voltage-gated calcium channels by cholinergic and adrenergic agonists in adult

  • 출판일1999.03
  • 저자
  • 서지사항
  • 등록일 2016.11.02
  • 조회수 552
the hippocampal formation has been a popular preparation with cellular neurophysiologists. the widespread use of the in vitro hippocampal slice preparation is at least partially due to its unique structure in which the cell bodies of the primary cell types and their major synaptic connections are arranged in layers transverse to the long axis of the hippocampus. the major intrinsic synaptic pathways (perforant path, mossy fibers, and schaffer collaterals), therefore, are largely preserved in transverse slices. in an attempt to overcome some of the difficulties associated with the application of traditional voltage-clamp techniques to cortical neurons, we have developed an adult hippocampal slice preparation in which the neurons, after treatment with proteolytic enzymes, are physically exposed and amenable to the use of patch-clamp recording techniques
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