In this study, two different types of liquid cooling garments are designed and their cooling effects are comparatively investigated. The tubing lengths and the inner layers of these garments are taken as the same, and the other parameters of the garments differed. In the outer layer of the garments, 10 × 3 rib and single jersey knitted wool fabrics are used. In the inner layer of the fabrics, cotton wound dressings are used. In one garment design, S- shaped sponges are used as the mid layer. For 10 × 3 rib the mid layer is obtained by three loops of 10 × 3 rib, and the outer layer is obtained by 10 loops of 10 × 3 rib, due to its three- dimensional structure. To test these garments, a thermal manikin and a chiller are developed. The effects of water inlet temperature and flow rate on the cooling effect are examined. Outer garments of 10 × 3 rib structure are found to provide effective cooling. When the water inlet temperature decreases, the effective cooling slightly increases. At lower flow rates, effective cooling increases slightly, while this effect disappears for higher flow rates.